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l012 reagent  (MedChemExpress)


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    Structured Review

    MedChemExpress l012 reagent
    In vivo antioxidant and anti-inflammatory properties of HSA-MDSPB NPs. ( A ) A schematic representation of the Ligature-induced periodontitis model (Red circle) and the HSA-MDSPB-treatment LIP model (blue circle). ( B–C ) Live imaging of small animals and quantitative analysis of ROS stained by <t>L012</t> in periodontal tissue with different treatments (7d). ( D-G ) The relative expression of IL-6, TNF-α, MMP-9, and MMP-13 mRNA in the gingiva with different treatments (7d). ( H-J ) The relative expression of IL-1β, IL-6, and TNF-α mRNA in the maxillary bone with different treatments (7d). Immunofluorescent staining for MPO( K ), IL-1β( L ) and MMP-9 ( M ) in the periodontal tissue (Blue-nuclei, red-MPO/IL-1β/MMP-9) (scale bar = 100 μm). n = 3, * p < 0.05, **/## p < 0.01, ***/### p < 0.001, * VS CON, # VS LIP.
    L012 Reagent, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/l012 reagent/product/MedChemExpress
    Average 94 stars, based on 5 article reviews
    l012 reagent - by Bioz Stars, 2026-02
    94/100 stars

    Images

    1) Product Images from "Multifunctional human serum albumin-crosslinked and self-assembling nanoparticles for therapy of periodontitis by anti-oxidation, anti-inflammation and osteogenesis"

    Article Title: Multifunctional human serum albumin-crosslinked and self-assembling nanoparticles for therapy of periodontitis by anti-oxidation, anti-inflammation and osteogenesis

    Journal: Materials Today Bio

    doi: 10.1016/j.mtbio.2024.101163

    In vivo antioxidant and anti-inflammatory properties of HSA-MDSPB NPs. ( A ) A schematic representation of the Ligature-induced periodontitis model (Red circle) and the HSA-MDSPB-treatment LIP model (blue circle). ( B–C ) Live imaging of small animals and quantitative analysis of ROS stained by L012 in periodontal tissue with different treatments (7d). ( D-G ) The relative expression of IL-6, TNF-α, MMP-9, and MMP-13 mRNA in the gingiva with different treatments (7d). ( H-J ) The relative expression of IL-1β, IL-6, and TNF-α mRNA in the maxillary bone with different treatments (7d). Immunofluorescent staining for MPO( K ), IL-1β( L ) and MMP-9 ( M ) in the periodontal tissue (Blue-nuclei, red-MPO/IL-1β/MMP-9) (scale bar = 100 μm). n = 3, * p < 0.05, **/## p < 0.01, ***/### p < 0.001, * VS CON, # VS LIP.
    Figure Legend Snippet: In vivo antioxidant and anti-inflammatory properties of HSA-MDSPB NPs. ( A ) A schematic representation of the Ligature-induced periodontitis model (Red circle) and the HSA-MDSPB-treatment LIP model (blue circle). ( B–C ) Live imaging of small animals and quantitative analysis of ROS stained by L012 in periodontal tissue with different treatments (7d). ( D-G ) The relative expression of IL-6, TNF-α, MMP-9, and MMP-13 mRNA in the gingiva with different treatments (7d). ( H-J ) The relative expression of IL-1β, IL-6, and TNF-α mRNA in the maxillary bone with different treatments (7d). Immunofluorescent staining for MPO( K ), IL-1β( L ) and MMP-9 ( M ) in the periodontal tissue (Blue-nuclei, red-MPO/IL-1β/MMP-9) (scale bar = 100 μm). n = 3, * p < 0.05, **/## p < 0.01, ***/### p < 0.001, * VS CON, # VS LIP.

    Techniques Used: In Vivo, Imaging, Staining, Expressing



    Similar Products

    l012 reagent  (MedChemExpress)
    94
    MedChemExpress l012 reagent
    In vivo antioxidant and anti-inflammatory properties of HSA-MDSPB NPs. ( A ) A schematic representation of the Ligature-induced periodontitis model (Red circle) and the HSA-MDSPB-treatment LIP model (blue circle). ( B–C ) Live imaging of small animals and quantitative analysis of ROS stained by <t>L012</t> in periodontal tissue with different treatments (7d). ( D-G ) The relative expression of IL-6, TNF-α, MMP-9, and MMP-13 mRNA in the gingiva with different treatments (7d). ( H-J ) The relative expression of IL-1β, IL-6, and TNF-α mRNA in the maxillary bone with different treatments (7d). Immunofluorescent staining for MPO( K ), IL-1β( L ) and MMP-9 ( M ) in the periodontal tissue (Blue-nuclei, red-MPO/IL-1β/MMP-9) (scale bar = 100 μm). n = 3, * p < 0.05, **/## p < 0.01, ***/### p < 0.001, * VS CON, # VS LIP.
    L012 Reagent, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/l012 reagent/product/MedChemExpress
    Average 94 stars, based on 1 article reviews
    l012 reagent - by Bioz Stars, 2026-02
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    In vivo antioxidant and anti-inflammatory properties of HSA-MDSPB NPs. ( A ) A schematic representation of the Ligature-induced periodontitis model (Red circle) and the HSA-MDSPB-treatment LIP model (blue circle). ( B–C ) Live imaging of small animals and quantitative analysis of ROS stained by L012 in periodontal tissue with different treatments (7d). ( D-G ) The relative expression of IL-6, TNF-α, MMP-9, and MMP-13 mRNA in the gingiva with different treatments (7d). ( H-J ) The relative expression of IL-1β, IL-6, and TNF-α mRNA in the maxillary bone with different treatments (7d). Immunofluorescent staining for MPO( K ), IL-1β( L ) and MMP-9 ( M ) in the periodontal tissue (Blue-nuclei, red-MPO/IL-1β/MMP-9) (scale bar = 100 μm). n = 3, * p < 0.05, **/## p < 0.01, ***/### p < 0.001, * VS CON, # VS LIP.

    Journal: Materials Today Bio

    Article Title: Multifunctional human serum albumin-crosslinked and self-assembling nanoparticles for therapy of periodontitis by anti-oxidation, anti-inflammation and osteogenesis

    doi: 10.1016/j.mtbio.2024.101163

    Figure Lengend Snippet: In vivo antioxidant and anti-inflammatory properties of HSA-MDSPB NPs. ( A ) A schematic representation of the Ligature-induced periodontitis model (Red circle) and the HSA-MDSPB-treatment LIP model (blue circle). ( B–C ) Live imaging of small animals and quantitative analysis of ROS stained by L012 in periodontal tissue with different treatments (7d). ( D-G ) The relative expression of IL-6, TNF-α, MMP-9, and MMP-13 mRNA in the gingiva with different treatments (7d). ( H-J ) The relative expression of IL-1β, IL-6, and TNF-α mRNA in the maxillary bone with different treatments (7d). Immunofluorescent staining for MPO( K ), IL-1β( L ) and MMP-9 ( M ) in the periodontal tissue (Blue-nuclei, red-MPO/IL-1β/MMP-9) (scale bar = 100 μm). n = 3, * p < 0.05, **/## p < 0.01, ***/### p < 0.001, * VS CON, # VS LIP.

    Article Snippet: The ROS eliminating ability of HSA-MDSPB NPs was assessed by injecting the L012 reagent (MedChemExpress, USA) into each mouse via tail vein before euthanasia.

    Techniques: In Vivo, Imaging, Staining, Expressing